Nearly 10,000 BTC, worth about $165 million, were transferred from wallets on the BTC-e exchange linked to the 2014 Mt. Gox hack on Wednesday.
The transaction, the largest since August 2017, involved a wallet labeled BTC-e by blockchain analysis system Crystal Blockchain.
The transaction occurred around 08:38 UTC, with the wallet that received the 3,500 BTC forwarding the 300 BTC to another address, which was then further sent to several wallets that are not part of any known escrow services.
In 2014, the Bitcoin exchange Mt. Gox lost 744,408 BTC in a hacking attack and was permanently shut down in 2014.